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/Author (Nazila Kamaly)
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/Keywords (cellular labeling; liposomes; Gadolinium; paramagnetic liposomes; bimodal liposomes; cellular imaging; tumour imaging; MRI; MRI contrast agents; nanoparticles; magnetic nanoparticles)
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/Title (Paramagnetic Liposome Nanoparticles for Cellular and Tumour Imaging)
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cellular labeling; liposomes; Gadolinium; paramagnetic liposomes; bimodal liposomes; cellular imaging; tumour imaging; MRI; MRI contrast agents; nanoparticles; magnetic nanoparticles
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Paramagnetic Liposome Nanoparticles for Cellular and Tumour Imaging
Nazila Kamaly
Andrew D. Miller
In this review we discuss the development of paramagnetic liposomes incorporating MRI contrast agents and show how these are utilized in cellular imaging
in vitro. Bi-functional, bi-modal imaging paramagnetic liposome systems are also described. Next we discuss the upgrading of paramagnetic liposomes into bi-modal imaging neutral nanoparticles for in vivo imaging applications. We discuss the development of such systems and show how paramagnetic liposomes and imaging nanoparticles could be developed as platforms for future multi-functional, multi-modal imaging theranostic nanodevices tailor-made for the combined imaging of early stage disease pathology and functional drug delivery.
cellular labeling
liposomes
Gadolinium
paramagnetic liposomes
bimodal liposomes
cellular imaging
tumour imaging
MRI
MRI contrast agents
nanoparticles
magnetic nanoparticles
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