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Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion
Daniel Ley
Sara Pereira
Lasse Ebdrup Pedersen
Johnny Arnsdorf
Hooman Hefzi
Anne Mathilde Davy
Tae Kwang Ha
Tune Wulff
Helene Faustrup Kildegaard
Mikael Rørdam Andersen
Chinese hamster ovary cells
Lactate
Ammonium
AA catabolism
CRISPR
Metabolic network reconstruction
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